Wrapping up the year by celebrating the Top 10 Ainslie Lab papers (by citations + social buzz).
Highlights include inverse vaccination for MS, intranasal flu vaccines, glioblastoma scaffolds, machine-learning-guided polymer design, and biodegradable immunomodulators taking the #1 spot.
Proud of this team and grateful for our collaborators. Here’s to another year of impactful immunoengineering!
10. Clark et al. Antigen-Specific Inverse Vaccination Strategies Using Particle Systems for Multiple Sclerosis. ACS Biomaterials Science & Engineering. https://lnkd.in/evXvhvZx
9. Pena et al. Optimizing delivery in a multivalent subunit influenza vaccine using mixed polymeric microparticle degradation rates. Journal of Controlled Release. https://lnkd.in/euwp3SsJ
8. Graham-Gurysh et al. Post-resection delivery of a TLR7/8 agonist from a biodegradable scaffold achieves immune-mediated glioblastoma clearance and protection against tumor challenge in mice. Nature Communication. https://lnkd.in/e735xCU9
7. Woodring et al. Biodegradable nanofibrous scaffolds enhance standard of care for glioblastoma via localized targeted therapy. Journal of Controlled Release. https://lnkd.in/eGxmGgtt
6. Williamson et al. Acetalated dextran: a novel delivery platform for particle-based vaccines. Expert Opinion on Drug Delivery. https://lnkd.in/e8ghPMpZ
5. Ontiveros-Padilla et al. Broadly active intranasal influenza vaccine with a nanocomplex particulate adjuvant targeting mast cells and toll-like receptor 9. Journal of Controlled Release. https://lnkd.in/eFTG57sd
4. Murphy et al. Mast cell activators as adjuvants for intranasal mucosal vaccines. International Journal of Pharmaceutics https://lnkd.in/eEJ_iJy4
3. Stiepel et al. Induction of Antigen-Specific Tolerance in a Multiple Sclerosis Model without Broad Immunosuppression. ACS Nano. https://lnkd.in/eRgYfBZk
2. Woodring et al. Supervised machine learning for predicting drug release from acetalated dextran nanofibers. Biomaterial Science. https://lnkd.in/e5YMRQuY
1. Barbery et al. Biodegradable Polymers for Application as Robust Immunomodulatory Biomaterial Carrier Systems. Small. https://lnkd.in/epYFBWpX