SUBSTACK

Lab organization | Tiny Technologies, Big Impact: A History of Micro- and Nanomedicine | Women and URMs in Drug Delivery | Cancer Immunology | Vaccines |  Controlled Release Systems | AI and Grant writing | Grad students and Post Docs | Polymers, Polymer Families and Co-polymer in Biomedical Research

I’ve created a SubStack to share some of my knowledge. Kristy Engineers Immunity: https://substack.com/@ainslielab

Lab organization

• Practical Systems That Keep My Academic Lab Running: Lessons learned from building a collaborative, accountable lab – https://go.unc.edu/SStManagement
• Four simple, real-life tips I use to keep my inbox under control: A practical system for staying responsive without drowning in email – https://go.unc.edu/SStEmail

Tiny Technologies, Big Impact: A History of Micro- and Nanomedicine

• Article 1 of 8: Living Medicines – https://go.unc.edu/SStLivingMed1
• Article 2 of 8: Complex Biologic Carriers – https://go.unc.edu/SStComplexBio2
• Article 3 of 8: Inorganic carriers – https://go.unc.edu/SStInorganic
• Article 4 of 8: Other Carriers – https://go.unc.edu/SStOtherCarriers
• Article 5 of 8: Nucleic Acids and Lipids – https://go.unc.edu/SStNALipids
• Article 6 of 8: Nucleic Acids and Lipids – https://go.unc.edu/SStPolymer
• Article 7 of 8: Protein carriers – https://go.unc.edu/SStProtein
• Article 8 of 8: Devices – https://go.unc.edu/SStDevices

Women and URMs in Drug Delivery

• The Leaky Pipeline Nobody Talks About: Women in Drug Delivery Research: A dispatch from the uncomfortable intersection of science and gender –link
• The “Baby Penalty” is Real (and It’s Worse Than We Thought) – link
• Who Gets to Do the Science? Underrepresented Groups in Drug Delivery – link

Cancer Immunology

• Cancer Immunotherapy: Training Your Body to Fight Back – https://go.unc.edu/SStImmunotherapy
• Cancer Vaccines: Why Your Immune System Needs a Map to Find Tumors – https://go.unc.edu/SStCancerVaccine
• The Marksman’s Approach: How Antibodies Became Cancer’s Worst Enemy – https://go.unc.edu/SStAntibody
• The Off Switch Problem: Why Brake Drugs Beat Accelerators – https://go.unc.edu/SStCheckpoint
• The Chemical Messaging System: How Cytokines Supercharge (or Sabotage) Your Immune System – https://go.unc.edu/SStCytokines
• The Science Fiction Cure: CAR T Cells (and Why They’re Terrifyingly Effective) – link

Vaccines

• Your immune system needs a delivery driver – link
• Tiny Packages, Big Impact: Why Scientists Are Shrinking Vaccines Down to Nano-Size – link
• A Field Guide to Adult Vaccines: Shingles, Flu, RSV, and Everything In Between – link
• Not All Vaccines Are Created Equal – And That’s a Good Thing – link
• The $150 Million Question: Why Your Vaccines Need to Chill (And What is Being Done About It) – link
• The Vaccine That Could End Flu Season Forever – link

Controlled release systems

• Why Some Drugs Work for 4 Hours – and Others for 4 Weeks: A plain-language guide to immediate vs. modified release medicines – https://go.unc.edu/SStControlledRelease
• The “Slow-Release” Revolution: How Polymers and AI Are Changing Medicine – link
• Your Lungs: A Built-In Delivery Platform – link
• Your Skin Is a Bouncer, and Drugs Are Trying to Get Into the Club – link
• Aerosols, Alveoli, and the Art of Pulmonary Drug Delivery – link
• Down There Drug Delivery – https://ainslielab.substack.com/p/down-there-drug-delivery?r=6f2o0o
• Your Eye Drop Is Doing a Lot More (And Less) Than You Think – link
• The Math Behind Your Medicine – link
• The Great Nanomedicine Debate: Why Your “Smart” Drug Delivery Might Not Be So Smart After All – link
• Why Tiny Particles Are Bouncing Around (And Why You Should Care) – link
• The Wild Evolution of Birth Control: From Ancient Egyptian Remedies to Smart Drug Delivery – link
• Why Nanoformulations Are a Complicated Technology – link

Grant writing and AI

• Why Some Drugs Work for 4 Hours – and Others for 4 Weeks: A plain-language guide to immediate vs. modified release medicines – https://go.unc.edu/SStControlledRelease
• The “Slow-Release” Revolution: How Polymers and AI Are Changing Medicine – link
• Your Lungs: A Built-In Delivery Platform – link
• Your Skin Is a Bouncer, and Drugs Are Trying to Get Into the Club – link
• Aerosols, Alveoli, and the Art of Pulmonary Drug Delivery – link
• Down There Drug Delivery – link
• Your Eye Drop Is Doing a Lot More (And Less) Than You Think – link
• The Math Behind Your Medicine – link
• The Great Nanomedicine Debate: Why Your “Smart” Drug Delivery Might Not Be So Smart After All – link
• Why Tiny Particles Are Bouncing Around (And Why You Should Care) – link
• The Wild Evolution of Birth Control: From Ancient Egyptian Remedies to Smart Drug Delivery – lab
• Why Nanoformulations Are a Complicated Technology – lab

Grad students and post docs

• How to interview for STEM graduate programs: https://go.unc.edu/STEMGradInterviews
• The Decision That Shapes Your PhD More Than Any Other: How to evaluate advisors, labs, and programs with clarity and intention – https://go.unc.edu/SStGradSelection
• Why I’ve Rejected Hundreds of CVs for Post Doc Positions: I have reviewed hundreds of CVs – here is what makes them stand out – https://go.unc.edu/SStPostDoc
• The Tenure-Track Job Market Is a Game. Here’s How to Play It: What nobody tells you before you apply for your first faculty position – https://go.unc.edu/SStTTJob

Polymers, Polymer Families and Co-polymer in Biomedical Research

• The Chemists Who Accidentally Invented the Future: Polymers Before WWI (1859–1909) – link
• When Germany Ruled Polymer Chemistry: The Plastics Explosion (1912–1939) – link
• America Takes the Wheel: The Postwar Polymer Boom (1948–1966) – link
• Designing for the Body: The Biomedical Decade (1969–1983) – link
• The Nanomedicine Revolution: Modern Polymers (1986–2013) – link