We show that peak immune responses are reached using particles that degrade at different rates by encapsulating vaccine elements, antigen and adjuvant, in particles that degrade at fast, medium, and slow rates and observing their immune responses. https://authors.elsevier.com/a/1WUtKcI2~mAaa
The Ainslie Lab almost sweeps the awards for the Pharmacoengineering and Molecular Pharmaceutics Research Symposium! Congrats to Naihan, Kathryn, and Erica.
Our latest publication uses nanofibrous acetalated dextran scaffolds to slowly release the chemotherapeutic doxorubicin in the resection cavity made after the surgical removal of glioblastoma. In collaboration with Dr. Shawn Hingtgen. http://pubs.acs.org/d…/pdf/10.1021/acs.molpharmaceut.7b01114
Highlights from our lab holiday party. The gift exchange was a hit!
We report superior encapsulation of STING agonist cGAMP in Ac-DEX microparticles and its formulation and evaluation as an influenza vaccine that provides long-acting protection. https://www.ncbi.nlm.nih.gov/m/pubmed/29170142
Congrats to Rebeca Thweatt for winning 2nd place at the American Institute of Chemical Engineers (AIChE) National Meeting for her poster “Drug Release of Paclitaxel from Ace-DEX Particles: an Experimental and Mathematical Model”!
Rebeca presented a poster on her summer research which was focused on modeling drug release from Ac-DEX nanoparticles.
Congrats to Kathryn Moore for receiving a poster award at Biomedical Engineering Society – BMES for her poster titled: Biocompatible Electrospun Nanofibrous Scaffolds Enhance Tumoricidal Stem Cell Therapy in Surgical Model of Glioblastoma Resection and Recurrence. With work in collaboration with Dr. … Read more
Congrats to Kathryn Moore for winning best poster at the UNC/NC State joint Biomedical Engineering annual retreat.
Dr. Ainslie is presenting as part of the UNC School of Dentistry Oral Biology Seminar Series on Tuesday 10/3 @ 1-2 p.m. in Koury 5615.
